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摘要翻译：
由于肥胖是许多严重疾病如糖尿病的危险因素，对肥胖和饮食失调的更好理解已经引起神经生物学、精神病学和神经经济学的关注。本文结合成瘾与肥胖的经济理论（Becker and Murphy，1988；Levy2002；Dragone2009)，以及神经经济学和神经生物学中有关肥胖与成瘾的最新研究结果，提出了今后的研究方向。提示神经生物学底物如脂联素、多巴胺(D2受体）、内源性大麻素、ghrelin、瘦素、nesfatin-1、去甲肾上腺素、食欲素、催产素、血清素、加压素、CCK、GLP-1、MCH、PYY和应激激素（如CRF）在脑（如OFC、VTA、NAcc和下丘脑）中可能决定肥胖经济学理论中的参数。同时，强调了在Tsallis统计的基础上引入时间不一致和收益/损失不对称的时间折扣（跨期选择）模型，并将时间知觉参数纳入神经经济学理论的重要性。讨论了该理论在分子水平上应用于肥胖的神经经济学和神经精神病学研究的未来方向，这可能有助于肥胖的医学/精神药理学治疗（如西布曲明）。
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英文标题：
《Toward molecular neuroeconomics of obesity》
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作者：
Taiki Takahashi
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最新提交年份：
2011
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分类信息：
一级分类：Quantitative Biology 数量生物学
二级分类：Neurons and Cognition 神经元与认知
分类描述：Synapse, cortex, neuronal dynamics, neural network, sensorimotor control, behavior, attention
突触，皮层，神经元动力学，神经网络，感觉运动控制，行为，注意
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一级分类：Quantitative Biology 数量生物学
二级分类：Other Quantitative Biology 其他定量生物学
分类描述：Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要：
Because obesity is a risk factor for many serious illnesses such as diabetes, better understandings of obesity and eating disorders have been attracting attention in neurobiology, psychiatry, and neuroeconomics. This paper presents future study directions by unifying (i) economic theory of addiction and obesity (Becker and Murphy, 1988; Levy 2002; Dragone 2009), and (ii) recent empirical findings in neuroeconomics and neurobiology of obesity and addiction. It is suggested that neurobiological substrates such as adiponectin, dopamine (D2 receptors), endocannabinoids, ghrelin, leptin, nesfatin-1, norepinephrine, orexin, oxytocin, serotonin, vasopressin, CCK, GLP-1, MCH, PYY, and stress hormones (e.g., CRF) in the brain (e.g., OFC, VTA, NAcc, and the hypothalamus) may determine parameters in the economic theory of obesity. Also, the importance of introducing time-inconsistent and gain/loss-asymmetrical temporal discounting (intertemporal choice) models based on Tsallis' statistics and incorporating time-perception parameters into the neuroeconomic theory is emphasized. Future directions in the application of the theory to studies in neuroeconomics and neuropsychiatry of obesity at the molecular level, which may help medical/psychopharmacological treatments of obesity (e.g., with sibutramine), are discussed.
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PDF链接：
https://arxiv.org/pdf/1111.6494
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