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摘要翻译：
对称性概念在物理学中的重要性是公认的：遗传密码也是如此吗？本着这种精神，几年前提出了一种基于连续对称的遗传密码模型，称为“晶体基模型”。本文综述了该模型、它的一些初步应用以及它的最新发展。事实上，在对我们的数学模型进行了有动机的介绍之后，我们通过将其应用于密码子使用概率求和规则的阐述和验证，以及在氨基酸的物理化学性质之间建立关系和一些预测来说明它的相关性。然后，在这种情况下，为核苷酸和密码子定义一个“生物自旋”结构，一对密码子-反密码子之间的相互作用可以简单地用（生物）自旋-自旋电位来表示。这一方法将构成论文的第二部分，在这里，通过引入最小能量原理，可以对遗传密码的进化进行分析，并与公认的方案很好地一致。对这种相互作用模型的更精确的研究提供了密码子偏见的信息，与数据一致。
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英文标题：
《Symmetry and Minimum Principle at the Basis of the Genetic Code》
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作者：
A. Sciarrino and P.Sorba
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最新提交年份：
2017
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分类信息：
一级分类：Quantitative Biology 数量生物学
二级分类：Other Quantitative Biology 其他定量生物学
分类描述：Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要：
The importance of the notion of symmetry in physics is well established: could it also be the case for the genetic code? In this spirit, a model for the Genetic Code based on continuous symmetries and entitled the "Crystal Basis Model" has been proposed a few years ago. The present paper is a review of the model, of some of its first applications as well as of its recent developments. Indeed, after a motivated presentation of our mathematical model, we illustrate its pertinence by applying it for the elaboration and verification of sum rules for codon usage probabilities, as well as for establishing relations and some predictions between physical-chemical properties of amino-acids. Then, defining in this context a "bio-spin" structure for the nucleotides and codons, the interaction between a couple of codon-anticodon can simply be represented by a (bio) spin-spin potential. This approach will constitute the second part of the paper where, imposing the minimum energy principle, an analysis of the evolution of the genetic code can be performed with good agreement with the generally accepted scheme. A more precise study of this interaction model provides informations on codon bias, consistent with data.
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PDF链接：
https://arxiv.org/pdf/1704.00940
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