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Multilevel Modelling of Medical Data using MLwiN.pdf
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STATISTICS IN MEDICINE
Statist. Med. 2002; 21:3291–3315 (DOI: 10.1002/sim.1264)
TUTORIAL IN BIOSTATISTICS
Multilevel modelling of medical data
Harvey Goldstein;, William Browne and Jon Rasbash
Institute of Education; University of London; London; U.K.
SUMMARYThis tutorial presents an overview of multilevel or hierarchical data modelling and its applications in medicine. A description of the basic model for nested data is given and it is shown how this can be extended to flexible models for repeated measures data and more complex structures involving cross-classications and multiple membership patterns within the software package MLwiN. A variety of response types are covered and both frequentist and Bayesian estimation methods are described.
Copyright: John Wiley & Sons, Ltd.
KEY WORDS: complex data structures; mixed model, multilevel model; random eects model;
repeated measures
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