Hillary Clinton declares 2016 Democratic presidential bid
The overwhelming Democratic favourite, she had been expected to declare her candidacy for months.
In a video on her website, Mrs Clinton declared: "I am running for president".
"Americans have fought their way back from tough economic times," she said, "but the deck is still stacked in favour of those at the top.
"Everyday Americans need a champion and I want to be that champion," she added.
Hillary Clinton's second presidential bid marks the latest chapter in a unique political career and the BBC takes a look back at how it all started.
The video features a number of Americans talking about their hopes and aspirations.
It ends with Mrs Clinton saying: "So I'm hitting the road to earn your vote because it's your time and I hope you'll join me on this journey".
Mrs Clinton's team said would spend the next few weeks building up grassroots support in the early Democratic primary states; she tweeted that she is on her way to Iowa.
She is expected to hold her first rally, officially kicking off her campaign, in mid-May.
Mrs Clinton's presidential ambitions have been the worst-kept secret in US politics
[Analysis: Gary O'Donoghue, BBC News, Des Moines, Iowa]
The launch of Hillary Clinton's campaign for the presidency was meant to be low key.
It was meant to reflect the idea that it was all about ordinary Americans and the everyday concerns of the middle class.
But whether she likes it or not, Mrs Clinton is a huge name in politics and reinventing herself as the embodiment of change won't be easy.
True, she is unlikely to face any stiff competition from her own side for the nomination, but Republicans have been unrelenting in their attacks on her and that will only increase.
She will also have to find a convincing vision for America that will capture the imagination of the voters.
Elections are usually about the future and Mrs. Clinton has to prove that she's not all about the past.
Mrs Clinton has already had the backing of Mr Obama, who told a news conference at the Summit of the Americas in Panama on Saturday that she would make an "excellent president".
And her successor in the post of secretary of state, John Kerry, called her a "good friend", telling ABC's This Week programme she "did a terrific job of rebuilding alliances that had been shredded over the course of the prior years".
But the attacks from the Republicans have already begun.
Republican presidential contender Rand Paul criticised Mrs Clinton for her handling of a September 2012 attack on a US diplomatic compound in Benghazi, Libya, in which the US ambassador was among those killed.
He also said questions remained about funds received by a charity set up by Mr and Mrs Clinton.
Jeb Bush, former Florida Governor and brother of George W Bush who is also considering whether to stand as a Republican candidate, tweeted: "We must do better than Hillary."


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