two arm randomized clinical trials, 计算所需event数量。power=0.8,one-sided type I = 0.25,effect size = 1.75, in terms of ratio of mean lifetimes(不是median lifetime). Lognormal distributed times in both treatment and control. Equal sample allocation.
其他所需的前提条件(比如event rate等)均可自由设定。
求大神帮忙指点,具体的计算公式是如何推导的,越详细越好