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Abstract: This paper discussed the synthesis of ethyl bromodifluoroacetate and further explored the process of ethyl bromodifluoroacetate. Considering the factors such as profit, wastes¡¯ recycling and industrial production, 1£¬1-difluoro -1£¬2£¬2- trichloroethane was chosen as the raw material. The process followed as below: first, dehydrochlorination, second, bromination, and third esterification. The purity of the product was analyzed and detected by GC1690. The optimal reaction conditions as following: ethanol as solvent, 1.3 equivalent of sodium hydroxide for reaction, condensation reaction temperature was 50¡æ, the temperature of esterification was 35¡æ, the best yield of ethyl bromodifluoroacetate was 67%.
Key words: Ethyl bromodifluoroacetate; bromination; 1£¬1-difluoro -1£¬2£¬2- trichloroethane