[定量生物学] 渗透应力囊泡的孔隙动力学 [推广有奖]

摘要翻译：
我们提出了渗透应力囊泡的孔隙动力学理论。当含有一定浓度溶质的脂质体被置于溶质耗尽的介质中时，溶剂通过脂质双层的渗透流动导致囊泡膨胀和膜表面张力增加。这会导致膜破裂和热孔张开。根据溶质的内部浓度和囊泡的大小，孔隙可以迅速关闭或长期存在。我们发现，长寿命毛孔的寿命与脂质体的大小无关。长寿命孔隙的关闭之后是短寿命孔隙的快速闪烁式打开和关闭。我们的模型与红细胞幽灵中长寿命毛孔的观察是一致的。
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英文标题：
《Pore dynamics of osmotically stressed vesicles》
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作者：
Yan Levin and Marco A. Idiart
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最新提交年份：
2003
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分类信息：

一级分类：Physics        物理学
二级分类：Soft Condensed Matter        软凝聚态物质
分类描述：Membranes, polymers, liquid crystals, glasses, colloids, granular matter
膜，聚合物，液晶，玻璃，胶体，颗粒物质
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一级分类：Physics        物理学
二级分类：Other Condensed Matter        其他凝聚态物质
分类描述：Work in condensed matter that does not fit into the other cond-mat classifications
在不适合其他cond-mat分类的凝聚态物质中工作
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一级分类：Physics        物理学
二级分类：Statistical Mechanics        统计力学
分类描述：Phase transitions, thermodynamics, field theory, non-equilibrium phenomena, renormalization group and scaling, integrable models, turbulence
相变，热力学，场论，非平衡现象，重整化群和标度，可积模型，湍流
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一级分类：Quantitative Biology        数量生物学
二级分类：Other Quantitative Biology        其他定量生物学
分类描述：Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要：
  We present a theory for pore dynamics of osmotically stressed vesicles. When a liposome with an internal concentration of solute is placed inside a solute-depleted medium, an osmotic flow of solvent through the lipid bilayer leads to swelling of vesicle and to increase in membrane surface tension. This can result in membrane rupture and opening of thermal pores. Depending on the internal concentration of solute and the size of the vesicle, pores can close rapidly or be long-lived. We find that the life span of the long-lived pores scales non-trivially with the size of the liposome. Closure of the long-lived pore is followed by a rapid flicker-like opening and closing of short-lived pores. Our model is consistent with the observation of long-lived pores in red blood cell ghosts.
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PDF链接：
https://arxiv.org/pdf/cond-mat/0311350