抗肿瘤免疫治疗皮肤黑色素瘤的实验研究 全细胞GM-CSF疫苗

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摘要翻译：
在黑色素瘤实验模型上，对免疫、化疗和手术切除原发肿瘤结节等多种提高抗肿瘤治疗效率的方法进行了研究，并对抗肿瘤疫苗的治疗和预防应用进行了对比分析。据推测，预防性疫苗接种可以将肿瘤发病率降低70%。黑色素瘤的疫苗治疗和手术治疗的结合使疫苗的抗转移活性提高了43%。我们认为联合治疗将导致更有效的抗肿瘤反应。
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英文标题：
《Experimental Researches of Cutaneous Melanoma Immunotherapy by Antitumor
  Cell-Whole GM-CSF-Producing Vaccines》
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作者：
I.V. Manina, N.M. Peretolchina, N.S. Saprikina, A.M. Kozlov, I.N.
  Mikhaylova, A.Yu.Barishnikov
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最新提交年份：
2011
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分类信息：

一级分类：Quantitative Biology        数量生物学
二级分类：Other Quantitative Biology        其他定量生物学
分类描述：Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要：
  Various approaches to increase efficiency of antitumor therapy by a combination of vaccinotherapy, chemotherapy and surgical excision of primary tumor nodes, and also the comparative analyses of therapeutic and preventive application of antitumoral vaccines were carried out in melanoma experimental model. It was postulated that preventive vaccination is able to prevent tumor incidence by 70 %. The combination of vaccinotherapy and surgical treatment of melanoma increases antimetastatic activity of vaccination by 43 %. We conclude the combined therapy would lead to more effective antitumor response.
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PDF链接：
https://arxiv.org/pdf/1110.2966

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关键词：黑色素瘤 黑色素 Quantitative Experimental QUANTITATIV therapy Experimental 分析 接种 vaccinotherapy