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摘要翻译：
这篇论文广泛地关注生命问题的起源，追求一种联合的方法，将对这个问题的一般哲学/概念反思与更详细和正式的以概念视角为导向的科学建模工作结合起来。中心的主题是作为具有适当细胞组织的更复杂系统的前驱物的分块化学的出现和维持。鉴于生命的进化概念主导了益生化学研究，并蔓延到原细胞领域，本文认为生命现象的“自主系统观点”是一个合适的--可以说是最合适的--概念框架作为原细胞研究的背景。自主性方法允许仔细和彻底地重新表述细胞生命问题的起源，即存在于所有成熟细胞中的集成的自生化学组织是如何从更简单的远离平衡的化学聚集系统中起源和发展的问题。
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英文标题：
《Modelling Early Transitions Toward Autonomous Protocells》
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作者：
Benjamin John Shirt-Ediss
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最新提交年份：
2016
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分类信息：
一级分类：Quantitative Biology 数量生物学
二级分类：Other Quantitative Biology 其他定量生物学
分类描述：Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要：
This thesis broadly concerns the origins of life problem, pursuing a joint approach that combines general philosophical/conceptual reflection on the problem along with more detailed and formal scientific modelling work oriented in the conceptual perspective developed. The central subject matter addressed is the emergence and maintenance of compartmentalised chemistries as precursors of more complex systems with a proper cellular organization. Whereas an evolutionary conception of life dominates prebiotic chemistry research and overflows into the protocells field, this thesis defends that the 'autonomous systems perspective' of living phenomena is a suitable - arguably the most suitable - conceptual framework to serve as a backdrop for protocell research. The autonomy approach allows a careful and thorough reformulation of the origins of cellular life problem as the problem of how integrated autopoietic chemical organisation, present in all full-fledged cells, originated and developed from more simple far-from-equilibrium chemical aggregate systems.
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PDF链接：
https://arxiv.org/pdf/1606.03620
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