1. Taken together, our data provide new mechanistic insights into possible endogenous
signaling metastatic signaling pathways involved in maintaining proliferation and
migration of breast cancer cells.
2. We sought to determine whether seliciclib (CYC202, R‐roscovitine) could increase the
antitumor effects of doxorubicin, with no increase in toxicity, in an MCF7 breast
cancer xenograft model.
3. MIB1 (ki67) immunohistochemistry demonstrated reduced proliferation with
treatment.
4. Surv ...


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