[数据] Methods and Applications of Sample Size Calculation in the clinical trials [推广有奖]

[size=13.2835px]临床试验样本量计算
This book provides methods for sample size calculation and recalculation for a
wide range of scenarios encountered when planning clinical trials. To facilitate a
deeper understanding of the procedures, the derivations of the methods are pre
sented within a common general framework. Furthermore, application of the
methods is illustrated by real clinical trial examples and source code written in the
software R implementing the presented approaches is provided. In addition,
numerous hints are given to published contributions on the topic. By this, the book
aims at giving an up-to-date overview on sample size calculation and recalculation
addressing both application-oriented practitioners and biostatisticians who are also
interested in the theoretical background of the methods they apply.

Heidelberg, Germany
April 2020
Meinhard Kiese