发帖
雷达卡
摘要翻译：
对巨乌贼轴突传播动作电位的实验数据进行了相空间检验。电容电流和离子电流与电位的关系曲线显示了线性部分，提供了钠和钾通道的温度、时间速率和最大电导常数。识别了离子通道的一级相变。将时间速率引入Avrami方程中，得到了每个通道的一个与温度无关的无量纲常数，该常数的值接近精细结构常数。它还揭示了与温度无关的标度指数。有证据表明动作电位穿过铁电滞回线。这导致在动作电位峰值出现二级相变极化翻转，接着是钠通道的关闭和钾通道的开放，最后在达到静息电位时通过反转极化翻转来关闭环路。巨乌贼动作电位的这种迟滞回线的存在表明神经元可能具有两种稳定状态，这是记忆储存和提取的基础。
---
英文标题：
《Universal scaling and ferroelectric hysteresis regimes in the giant
squid axon propagating action potential: a Phase Space Approach》
---
作者：
Nikola K. Jurisic and Fred Cooper
---
最新提交年份：
2017
---
分类信息：
一级分类：Quantitative Biology 数量生物学
二级分类：Other Quantitative Biology 其他定量生物学
分类描述：Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
--
---
英文摘要：
The experimental data for the giant squid axon propagated action potential is examined in phase space. Plots of capacitive and ionic currents vs. potential exhibit linear portions providing temperature dependent time rates and maximum conductance constants for sodium and Potassium channels. First order phase transitions of ionic channels are identified. Incorporation of time rates into Avrami equations for fractions of open channels yields for each channel a temperature independent dimensionless constant that is close in value to the fine structure constant. It also reveals temperature independent scaling exponents. Evidence is presented that the action potential traverses a ferroelectric hysteresis loop. This results in a second order phase transition polarization flip at the peak of the action potential, followed by closing of sodium and opening of potassium channels, and finally closing the loop by reversing the polarization flip as the resting potential is reached. The existence of this hysteresis loop for the giant squid action potential suggests the possibility of neurons with two stable states, the basis for memory storage and retrieval.
---
PDF链接：
https://arxiv.org/pdf/1711.03575
京公网安备 11010802022788号
