摘要翻译:
当前的新型冠状病毒疫情严厉地提醒人们,无论是在单一的人类宿主中还是在跨大陆的感染浪潮中,病毒动力学往往是一个关于数字的故事。在这张快照中,我们的目标是为关键数字提供一个一站式、精心策划的图形来源,帮助我们理解驱动我们当前全球危机的病毒。讨论围绕着两个广泛的主题:1)病毒本身的生物学和2)单一人类宿主感染的特征。我们的一页总结提供了与新型冠状病毒有关的关键数字,主要基于同行审查的文献。以下附有说明的参考资料证实了以摘要格式报告的数字。读者被敦促记住,仍然存在许多不确定性,对这场流行病和驱动它的病毒的知识正在迅速发展。在下面的段落中,我们提供了“信封背面”的计算,这些计算举例说明了可以从了解一些关键数字和使用定量逻辑中获得的洞察力。这些计算有助于通过理智检查提高我们的直觉,但不能取代详细的流行病学分析。
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英文标题:
《SARS-CoV-2 (COVID-19) by the numbers》
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作者:
Yinon M. Bar-On, Avi I. Flamholz, Rob Phillips, Ron Milo
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最新提交年份:
2020
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分类信息:
一级分类:Quantitative Biology 数量生物学
二级分类:Other Quantitative Biology 其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要:
The current SARS-CoV-2 pandemic is a harsh reminder of the fact that, whether in a single human host or a wave of infection across continents, viral dynamics is often a story about the numbers. In this snapshot, our aim is to provide a one-stop, curated graphical source for the key numbers that help us understand the virus driving our current global crisis. The discussion is framed around two broad themes: 1) the biology of the virus itself and 2) the characteristics of the infection of a single human host. Our one-page summary provides the key numbers pertaining to SARS-CoV-2, based mostly on peer-reviewed literature. The numbers reported in summary format are substantiated by the annotated references below. Readers are urged to remember that much uncertainty remains and knowledge of this pandemic and the virus driving it is rapidly evolving. In the paragraphs below we provide "back of the envelope" calculations that exemplify the insights that can be gained from knowing some key numbers and using quantitative logic. These calculations serve to improve our intuition through sanity checks, but do not replace detailed epidemiological analysis.
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PDF链接:
https://arxiv.org/pdf/2003.12886