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摘要翻译：
自杀行为是世界范围内伤害和死亡的主要原因。自杀与抑郁症和精神分裂症等精神疾病以及经济不确定性和社会/文化因素有关。本研究提出自杀的神经经济学框架。神经经济学参数（例如，风险态度、概率加权、跨期选择中的时间折扣和损失厌恶）被预测与自杀行为有关。神经生物学和神经内分泌学底物，如5-羟色胺、多巴胺、皮质醇（HPA轴）、一氧化氮、血清胆固醇、肾上腺素、去甲肾上腺素、性腺激素（如雌二醇和孕酮）、脑区（如眶额叶/背外侧前额叶皮层和边缘区（如杏仁核）中的脱氢表雄酮(DHEA)可能与调节自杀风险的神经经济学参数有关。目前的框架为自杀行为背后的决策过程的“分子神经经济学”奠定了基础。
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英文标题：
《Neuroeconomics of suicide》
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作者：
Taiki Takahashi
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最新提交年份：
2011
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分类信息：
一级分类：Quantitative Biology 数量生物学
二级分类：Neurons and Cognition 神经元与认知
分类描述：Synapse, cortex, neuronal dynamics, neural network, sensorimotor control, behavior, attention
突触，皮层，神经元动力学，神经网络，感觉运动控制，行为，注意
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一级分类：Quantitative Biology 数量生物学
二级分类：Other Quantitative Biology 其他定量生物学
分类描述：Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要：
Suicidal behavior is a leading cause of injury and death worldwide. Suicide has been associated with psychiatric illnesses such as depression and schizophrenia, as well as economic uncertainty, and social/cultural factors. This study proposes a neuroeconomic framework of suicide. Neuroeconomic parameters (e.g., risk-attitude, probability weighting, time discounting in intertemporal choice, and loss aversion) are predicted to be related to suicidal behavior. Neurobiological and neuroendocrinological substrates such as serotonin, dopamine, cortisol (HPA axis), nitric oxide, serum cholesterol, epinephrine, norepinephrine, gonadal hormones (e.g., estradiol and progesterone), dehydroepiandrosterone (DHEA) in brain regions such as the orbitofrontal/dorsolateral prefrontal cortex and limbic regions (e.g., the amygdala) may supposedly be related to the neuroeconomic parameters modulating the risk of suicide. The present framework puts foundations for "molecular neuroeconomics" of decision-making processes underlying suicidal behavior.
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PDF链接：
https://arxiv.org/pdf/1111.6488
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