摘要翻译:
由于能源供应不足、技术专长有限和基础设施薄弱等挑战依然存在,发展中国家对负担得起的适当医疗技术的需求继续增加。低场MRI是一种技术,可以根据这些国家的具体成像需求进行定制。它的低功耗要求和在最低屏蔽或无屏蔽环境下工作的可能性使其特别具有吸引力。虽然这项技术已经在几十年里得到了广泛的应用,但在临床应用中,它是否能够诊断和改善患者的预后还有待证明。我们在这里展示了预极化MRI(PMRI)技术的稳健性,用于在发展中国家的组装和部署,以用于婴儿脑积水的具体应用。脑积水的治疗计划和管理需要适度的空间分辨率,只有大脑可以从脑实质内的液体组织对比细节中区分出来才是必要的。我们构建了一个基于Lee-Whiting线圈系统的内屏蔽PMRI系统,该系统直径为22厘米球形体积。在无屏蔽室内,通过引入足够大小的梯度场来控制读出场的5000ppm不均匀性,在113kHz下获得了面内分辨率为3mm×3mm的投影体模图像。低成本、简单的组装、部署潜力和维护要求证明了我们的PMRI系统适合发展中国家。低场MRI图像空间分辨率和对比度的进一步提高将使其在脑积水以外的潜在临床应用更加广泛。
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英文标题:
《Design of a sustainable pre-polarizing magnetic resonance imaging system
for infant hydrocephalus》
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作者:
Johnes Obungoloch, Joshua Harper, Steven Consevage, Igor Savukov,
Thomas Neuberger, Srinivas Tadigadapa, and Steven J. Schiff
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最新提交年份:
2018
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分类信息:
一级分类:Physics 物理学
二级分类:Medical Physics 医学物理学
分类描述:Radiation therapy. Radiation dosimetry. Biomedical imaging modelling. Reconstruction, processing, and analysis. Biomedical system modelling and analysis. Health physics. New imaging or therapy modalities.
放射治疗。辐射剂量学。生物医学成像建模。重建、处理和分析。生物医学系统建模与分析。健康物理学。新的成像或治疗方式。
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一级分类:Electrical Engineering and Systems Science 电气工程与系统科学
二级分类:Image and Video Processing 图像和视频处理
分类描述:Theory, algorithms, and architectures for the formation, capture, processing, communication, analysis, and display of images, video, and multidimensional signals in a wide variety of applications. Topics of interest include: mathematical, statistical, and perceptual image and video modeling and representation; linear and nonlinear filtering, de-blurring, enhancement, restoration, and reconstruction from degraded, low-resolution or tomographic data; lossless and lossy compression and coding; segmentation, alignment, and recognition; image rendering, visualization, and printing; computational imaging, including ultrasound, tomographic and magnetic resonance imaging; and image and video analysis, synthesis, storage, search and retrieval.
用于图像、视频和多维信号的形成、捕获、处理、通信、分析和显示的理论、算法和体系结构。感兴趣的主题包括:数学,统计,和感知图像和视频建模和表示;线性和非线性滤波、去模糊、增强、恢复和重建退化、低分辨率或层析数据;无损和有损压缩编码;分割、对齐和识别;图像渲染、可视化和打印;计算成像,包括超声、断层和磁共振成像;以及图像和视频的分析、合成、存储、搜索和检索。
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英文摘要:
The need for affordable and appropriate medical technologies for developing countries continue to rise as challenges such as inadequate energy supply, limited technical expertise and poor infrastructure persists. Low-field MRI is a technology that can be tailored to meet specific imaging needs within such countries. Its low power requirements and the possibility of operating in minimally shielded or unshielded environments make it especially attractive. Although the technology has been widely demonstrated over several decades, it is yet to be shown that it can be diagnostic and improve patient outcomes in clinical applications. We here demonstrate the robustness of pre-polarizing MRI (PMRI) technology for assembly and deployment in developing countries for the specific application to infant hydrocephalus. Hydrocephalus treatment planning and management requires modest spatial resolution, and only that the brain can be distinguished from fluid - tissue contrast detail within the brain parenchyma is not essential. We constructed an internally shielded PMRI system based on the Lee-Whiting coil system with a 22 cm diameter of spherical volume. In an unshielded room, projection phantom images were acquired at 113 kHz with in-plane resolution of 3 mm x 3 mm, by introducing gradient fields of sufficient magnitude to dominate the 5000ppm inhomogeneity of the readout field. The low cost, straightforward assembly, deployment potential, and maintenance requirements demonstrate the suitability of our PMRI system for developing countries. Further improvement in the image spatial resolution and contrast of low-field MRI will broaden its potential clinical utility beyond hydrocephalus.
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PDF链接:
https://arxiv.org/pdf/1803.09075


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