三维荧光显微图像合成及 分割

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摘要翻译：
荧光显微技术的发展使得获得更好的图像质量和更深入组织的三维图像体积成为可能。分割是描述和分析图像中生物结构的必要步骤，近年来利用深度学习进行三维分割取得了很好的效果。一个问题是，深度学习技术需要大量的groundtruth数据集，这对于大型3D显微镜体积的手工注释是不切实际的。本文提出了一种利用合成三维体进行训练的三维深度学习核分割方法。利用空间约束的循环一致对抗网络生成一组合成体和相应的地真值。分割结果表明，本文提出的方法能够成功地对各种数据集进行核分割。
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英文标题：
《Three Dimensional Fluorescence Microscopy Image Synthesis and
  Segmentation》
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作者：
Chichen Fu and Soonam Lee and David Joon Ho and Shuo Han and Paul
  Salama and Kenneth W. Dunn and Edward J. Delp
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最新提交年份：
2018
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分类信息：

一级分类：Computer Science        计算机科学
二级分类：Computer Vision and Pattern Recognition        计算机视觉与模式识别
分类描述：Covers image processing, computer vision, pattern recognition, and scene understanding. Roughly includes material in ACM Subject Classes I.2.10, I.4, and I.5.
涵盖图像处理、计算机视觉、模式识别和场景理解。大致包括ACM课程I.2.10、I.4和I.5中的材料。
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一级分类：Computer Science        计算机科学
二级分类：Machine Learning        机器学习
分类描述：Papers on all aspects of machine learning research (supervised, unsupervised, reinforcement learning, bandit problems, and so on) including also robustness, explanation, fairness, and methodology. cs.LG is also an appropriate primary category for applications of machine learning methods.
关于机器学习研究的所有方面的论文（有监督的，无监督的，强化学习，强盗问题，等等），包括健壮性，解释性，公平性和方法论。对于机器学习方法的应用，CS.LG也是一个合适的主要类别。
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一级分类：Electrical Engineering and Systems Science        电气工程与系统科学
二级分类：Image and Video Processing        图像和视频处理
分类描述：Theory, algorithms, and architectures for the formation, capture, processing, communication, analysis, and display of images, video, and multidimensional signals in a wide variety of applications. Topics of interest include: mathematical, statistical, and perceptual image and video modeling and representation; linear and nonlinear filtering, de-blurring, enhancement, restoration, and reconstruction from degraded, low-resolution or tomographic data; lossless and lossy compression and coding; segmentation, alignment, and recognition; image rendering, visualization, and printing; computational imaging, including ultrasound, tomographic and magnetic resonance imaging; and image and video analysis, synthesis, storage, search and retrieval.
用于图像、视频和多维信号的形成、捕获、处理、通信、分析和显示的理论、算法和体系结构。感兴趣的主题包括：数学，统计，和感知图像和视频建模和表示；线性和非线性滤波、去模糊、增强、恢复和重建退化、低分辨率或层析数据；无损和有损压缩编码；分割、对齐和识别；图像渲染、可视化和打印；计算成像，包括超声、断层和磁共振成像；以及图像和视频的分析、合成、存储、搜索和检索。
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英文摘要：
  Advances in fluorescence microscopy enable acquisition of 3D image volumes with better image quality and deeper penetration into tissue. Segmentation is a required step to characterize and analyze biological structures in the images and recent 3D segmentation using deep learning has achieved promising results. One issue is that deep learning techniques require a large set of groundtruth data which is impractical to annotate manually for large 3D microscopy volumes. This paper describes a 3D deep learning nuclei segmentation method using synthetic 3D volumes for training. A set of synthetic volumes and the corresponding groundtruth are generated using spatially constrained cycle-consistent adversarial networks. Segmentation results demonstrate that our proposed method is capable of segmenting nuclei successfully for various data sets.
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PDF链接：
https://arxiv.org/pdf/1801.07198

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关键词：Segmentation Applications Mathematical Presentation Architecture large 循环 groundtruth nuclei 深度