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摘要翻译：
目的：一个相互矛盾的证据体表明，局限性牙周炎症在怀孕期间全身蔓延，导致不良妊娠结局。本系统回顾和荟萃分析旨在特异性地评价牙周炎和子痫前期之间的关系。方法：在Medline、Pubmed、Cochrane对照临床试验注册表中进行电子检索，以识别和选择分析牙周病与子痫前期相关性的观察性病例对照和队列研究。遵循了Prisma准则和Moose核对表。结果：共选取30项研究，其中6项队列研究和24项病例对照研究。牙周炎与先兆子痫的风险增加显著相关，尤其是在包括队列研究和中低收入国家的亚组分析在内的亚组分析中。结论：牙周炎似乎是先兆子痫的一个重要危险因素，这在中低收入国家可能更加明显。
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英文标题：
《Periodontitis and preeclampsia in pregnancy: A systematic review and
meta-analysis》
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作者：
Quynh-Anh Le, Rahena Akhter, Kimberly M. Coulton, Ngoc T.N Vo, Le T.Y
Duong, Hoang V. Nong, Albert Yaacoub, George Condous, Joerg Eberhard and
Ralph Nanan
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最新提交年份：
2021
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分类信息：
一级分类：Quantitative Biology 数量生物学
二级分类：Other Quantitative Biology 其他定量生物学
分类描述：Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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一级分类：Quantitative Biology 数量生物学
二级分类：Quantitative Methods 定量方法
分类描述：All experimental, numerical, statistical and mathematical contributions of value to biology
对生物学价值的所有实验、数值、统计和数学贡献
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英文摘要：
Objectives: A conflicting body of evidence suggests localized periodontal inflammation to spread systemically during pregnancy inducing adverse pregnancy outcomes. This systematic review and meta-analysis aimed to specifically evaluate the relationship between periodontitis and preeclampsia. Methods: Electronic searches were carried out in Medline, Pubmed, Cochrane Controlled Clinical Trial Register to identify and select observational case-control and cohort studies that analyzed the association between periodontal disease and preeclampsia. Prisma guidelines and Moose checklist were followed. Results: Thirty studies including six cohorts and twenty-four case-control studies were selected. Periodontitis was significantly associated with increased risk for preeclampsia, especially in a subgroup analysis including cohort studies and subgroup analysis with lower-middle-income countries. Conclusion: Periodontitis appears as a significant risk factor for preeclampsia, which might be even more pronounced in lower-middle-income countries.
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PDF链接：
https://arxiv.org/pdf/2108.05186
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