楼主: Hollycherry
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how to get the MLE [推广有奖]

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楼主
Hollycherry 发表于 2011-9-10 03:44:31 |AI写论文

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I need some one help me. My question is ,
Given Xi (i=1,....n) is normal distribution with mean u1 and sd 1
Yi (i=1,....n) is normal distribution with mean u2 and sd 1
also given constraint u1 is smaller than u2

what's the Maximum likelihood estimate for u1 and u2

I know how to get the MLE without the constraint.
Please help me. Thank you

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关键词:Get How MLE The distribution question without normal Thank

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epoh 发表于3楼  查看完整内容

貌似是要求Maximum Likelihood estimation for a mixture of Gaussians For a mixture of different normal distributions (a Gaussian Mixture Model), the correct parameters for mean and standard deviation for each Gaussian cannot be computed by simply taking mean and std of the entire data set. The observed data must be divided into several Gaussians, each of with its own mean and standard devia ...

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沙发
Hollycherry 发表于 2011-9-10 07:47:22
再问一声有没有人知道?是不是很难解?

藤椅
epoh 发表于 2011-9-10 14:26:08

貌似是要求

Maximum Likelihood estimation for a mixture of Gaussians


For a mixture of different normal distributions (a Gaussian Mixture Model),
the correct parameters for mean and standard deviation for each Gaussian
cannot be computed by simply taking mean and std of the entire data set.
The observed data must be divided into several Gaussians,
each of with its own mean and standard deviation.
One approach for obtaining the paramaters for each Gaussian is to
apply the algorithm for Expectation Maximization.

  http://www.mathworks.com/help/toolbox/stats/gmdistribution.fit.html

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板凳
Hollycherry 发表于 2011-9-11 06:33:37
谢谢答复。
不是mixture of univariate normal distribution. 所有的Xi 和Yi are indepentent. 如没有constraint ( u1 is smaller than u2)的话, MLE for Xi and Yi are u1 and u2. With the constraint, I really don't know to solve it.

报纸
epoh 发表于 2011-9-11 08:02:08

假设

    X:mu1=3;sd1=7

      数据在matlab模拟产生

    Y:mu2=9;sd2=2

      数据在matlab模拟产生.

请问你要求甚么?

   graph.jpg

地板
Hollycherry 发表于 2011-9-12 10:07:30
我查了这应是保序回归(isotonic regression)。我需要的是如何推导出u1和u2的极大似然估计。多谢。

7
sunjian6696 发表于 2013-8-4 15:29:11
你好!我是天津医科大学的研究生,想向您请教关于保序回归的问题,一方面是原理,另一方面是其编程。我的问题是关于求LD50的。我们知道某种药物是有毒性的,因此实验从药物的最小剂量开始,x1,如果没有毒性反应则下一例上升一等级x2,如果有则下降一等级,直到出现7个交叉点。如何用保序回归求解?QQ592229626期待您的回复。

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