1 Biostatistics in Clinical Trials . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . | 1 |
in Drug Development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . | 71 |
3 Genomics and Bioinformatics in Biological Discovery
and Pharmaceutical Development . . . . . . . . . . . . . . . . . . . . . . . . . . . 105
Wendell Jones
4 Biostatistical Methods in Pharmacoepidemiology . . . . . . . . . . . . . . . 143
Ana Filipa Macedo, Ana Maria Rodriguez, William Hawkes,
and Alban Fabre
5 Causal Inference in Pharmacoepidemiology . . . . . . . . . . . . . . . . . . . 181
Ashley Buchanan, Tianyu Sun, and Natallia V. Katenka
6 Statistical Data Mining of Clinical Data . . . . . . . . . . . . . . . . . . . . . . 225
Ilya Lipkovich, Bohdana Ratitch, and Cristina Ivanescu
7 Segmentation and Choice Models . . . . . . . . . . . . . . . . . . . . . . . . . . . 317
Steven Blahut and Jeff Niemira
8 Modern Analytic Techniques for Predictive Modeling
of Clinical Trial Operations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361
Vladimir V. Anisimov
9 Better Together: Examples of Biostatisticians Collaborating
in Drug Development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 409
Russell Reeve, Seth Berry, and Brandon Swift


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