Eosinophils and Disease Pathogenesis
General
highly specialized granulocytic effector cells;produce and store diverse biologically active molecules;Transmigration→invasion→secretion→recruitment→marked and persistent →HEalterations in the microenvironment →chronic (and potentially irreversible) organ damage
Box 1. Major causes of hypereosinophilia Non-neoplastic reactive conditions (secondary/reactive HE)– Helminth infections– Scabies, other infestations– Allergic bronchopulmonary aspergillosis ...


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