you can read it here onlinehttp://books.google.com.hk/books?hl=zh-CN&lr=&id=JGfODSftpAEC&oi=fnd&pg=PA1&dq=Validating+clinical+trial+data+reporting+with+SAS&ots=LMLwHvvLoM&sig=ezYyumwZMbxNS85IP7DWu3QJRAg&redir_esc=y&hl=zh-CN&sourceid=cndr#v=onepage&q&f=false