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[问答] Can I exclude Insignificant Covariates from Cox Model? [推广有奖]

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楼主
ReneeBK 发表于 2014-4-12 02:18:41 |AI写论文

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I am using the Cox regression model to forecast failures of machines. I have several possible covariates. I ran the analysis in SPSS. The method I used to add covariates was backward stepwise (Wald). The table 'Variables in the Equation' shows that some covariates are not significant.Can I exclude the insignificant variable, rerun the Cox regression?


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关键词:significant covariates covariate Variates Variate machines backward possible question solution

沙发
ReneeBK 发表于 2014-4-12 02:19:14
The baseline hazard is usually estimated by the more straightforward Breslow or Kalbfleisch-Prentice methods

藤椅
ReneeBK 发表于 2014-4-12 02:23:57
It is not statistically correct to remove "insignificant" variables, just as stepwise regression (without penalization) is invalid. Much has been written about this topic.

板凳
ReneeBK 发表于 2014-4-12 02:24:44
How exactly are you creating forecasts from this model? Are you using smoothing spline estimates of the Schoenfeld residuals to estimate the baseline hazard function? If so, do you do this before or after eliminating "insignificant" variables? If your goal is prediction, some very prognostic markers may have inference on hazards ratios which are not significant

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