Pharmaceutical Statistics Using SAS.pdf
(3.6 MB, 需要: 6 个论坛币)
Analysis of Clinical Trials Using SAS: A Practical Guide
Written by
Alex Dmitrienko
Principal Research Scientist
Eli Lilly and Company
Geert Molenberghs
Professor of Statistics
Hasselt University
Christy Chuang-Stein
Executive Director
Pfizer
Walt Offen
Senior Research Fellow
Eli Lilly and Company
【书名】Pharmaceutical Statistics Using SAS: A Practical Guide
【作者】Alex Dmitrienko; Christy Chuang-Stein; Ralph B.; Sr.; Ph.d. D'agostino
【出版社】SAS Publishing
【版本】First edition
【出版日期】February 26, 2007
【文件格式】PDF (清晰电子书)
【文件大小】3.6M (解压后)
【页数】464 pages
【ISBN出版号】159047886X
【资料类别】SAS实用工具书
【市面定价】$56
【扫描版还是影印版】清晰电子书
【是否缺页】否
【关键词】beta regression model, proc glimmix, Wilcoxon Rank Sum
【内容简介】 本书为制药领域专家撰写,介绍了如何将最新生物统计的技术应用于新药研发过程中。
【Amazon链接】
http://www.amazon.com/Pharmaceutical-Statistics-Using-SAS-Practical/dp/159047886X
【目录】
Chapter 1 Statistics in Drug Development
Chapter 2 Modern Classification Methods for Drug Discovery
Chapter 3 Model Building Techniques in Drug Discovery
Chapter 4 Statistical Considerations in Analytical Method Validation
Chapter 5 Some Statistical Considerations in Nonclinical Safety Assessment
Chapter 6 Nonparametric Methods in Pharmaceutical Statistics
Chapter 7 Optimal Design of Experiments in Pharmaceutical Applications
Chapter 8 Analysis of Human Pharmacokinetic Data
Chapter 9 Allocation in Randomized Clinical Trials
Chapter 10 Sample-Size Analysis for Traditional Hypothesis Testing: Concepts and Issues
Chapter 11 Design and Analysis of Dose-Ranging Clinical Studies
Chapter 12 Analysis of Incomplete Data
Chapter 13 Reliability and Validity: Assessing the Psychometric Properties of Rating Scales
Chapter 14 Decision Analysis in Drug Development
【整理书评】
本书通过一系列教程和实例介绍制药领域最新的数值分析技术,还提供了大量实用SAS Code用于解决实际问题。涉及的主题包括:
drug discovery experiments to identify promising chemical compounds
animal studies to assess the toxicological profile of these compounds
clinical pharmacology studies to examine the properties of new drugs in healthy human subjects
Phase II and Phase III clinical trials to establish therapeutic benefits of experimental drugs


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