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Editorial Reviews Product Description Quantitativetrait locus (QTL) mapping is used to discover the genetic and moleculararchitecture underlying complex quantitative traits. It has importantapplications in agricultural, evolutionary, and biomedical research.R/qtl is an extensible, interactive environment for QTL mapping inexperimental crosses. It is implemented as a package for the widelyused open source statistical software R and contains a diverse array ofQTL mapping methods, diagnostic tools for ensuring high-quality data,and facilities for the fit and exploration of multiple-QTL models,including QTL x QTL and QTL x environment interactions. This book is acomprehensive guide to the practice of QTL mapping and the use ofR/qtl, including study design, data import and simulation, datadiagnostics, interval mapping and generalizations, two-dimensionalgenome scans, and the consideration of complex multiple-QTL models. Twomoderately challenging case studies illustrate QTL analysis in itsentirety.
The book alternates between QTL mapping theory andexamples illustrating the use of R/qtl. Novice readers will finddetailed explanations of the important statistical concepts and,through the extensive software illustrations, will be able to applythese concepts in their own research. Experienced readers will finddetails on the underlying algorithms and the implementation ofextensions to R/qtl. There are 150 figures, including 90 in full color.
Product Details
- Hardcover: 400 pages
- Publisher: Springer; 1 edition (July 20, 2009)
- Language: English
- ISBN-10: 0387921249
- ISBN-13: 978-0387921242
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