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[定量生物学] peppychains:简化3D打印的普通蛋白质的组装 模型 [推广有奖]

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可人4 在职认证  发表于 2022-3-3 19:46:00 来自手机 |AI写论文

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摘要翻译:
Peppytides是一种粗粒、精确的多肽链物理模型。我已经在2014年1月的make杂志上分享了制作你自己的多肽链和Peppytides的STL文件的说明。然而,Peppytides涉及到很多步骤和单元的组装。人们问我,'有没有更简单的方法来制作这些模型?‘。我参加了几个研讨会,实践会议,演讲和一个与Peppytides的科学活动。从我从各处得到的反馈来看,大多数制造商、教师和学生都想要3D打印的东西,或者至少更容易制作,即使是以牺牲一些功能为代价。我已经设计了一个新版本的模型,命名为PeppyChains,其中模型的主干链可以作为一个单一的单元进行3D打印。PeppyChains的设计消除了部件的组装以形成主干链,但代价是失去了使用偏置磁铁来支持主干中某些phi/psi角的能力。我已经在各种讲座和研讨会上演示了PeppyChains,以及Peppytides,我收到了公开STL文件的请求。根据流行的需求,我在这里分享这个STL,并提供一步一步的说明来制作peppychains。只要添加氢键磁铁,油漆和颜色编码原子,你就准备好了!不许钻孔。没有耗时的组装。
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英文标题:
《PeppyChains: Simplifying the assembly of 3D-printed generic protein
  models》
---
作者:
Promita Chakraborty
---
最新提交年份:
2015
---
分类信息:

一级分类:Quantitative Biology        数量生物学
二级分类:Other Quantitative Biology        其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
--

---
英文摘要:
  Peppytides is a coarse-grained, accurate, physical model of the polypeptide chain. I have shared instructions to make your own polypeptide chain and STL files of Peppytides in MAKE magazine in Jan 2014 issue. However, Peppytides involves a lot of steps and assembly of units. People were asking me, 'Is there any easier way to make these models?'. I have been at several workshops, hands-on sessions, talks and a science events with Peppytides. From the feedback that I got everywhere, most of the makers, teachers and students want something that is 3D-Print-&-Go, or at least easier to make, even at the cost of some features.   I have designed a new version of the model, named PeppyChains, in which the backbone chain of the model can be 3d-printed as a single unit. PeppyChains design eliminates the assembling of parts to form the backbone chain, but with the cost of losing the ability to use bias-magnets to favor certain phi/psi angles in the backbone. I have been demonstrating PeppyChains at various talks and workshops along with Peppytides, and I have received requests for making the STL file public. On popular demand, here I am sharing this STL and providing the step-by-step instructions to make PeppyChains. Just add the hydrogen-bond magnets, paint and color-code the atoms, and you are ready to go! No drilling. No time consuming assembly.
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PDF链接:
https://arxiv.org/pdf/1605.04166
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关键词:Chains Chain 3D打印 蛋白质 Quantitative assembly chain 使用 制造商 实践

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