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摘要翻译：
交联质谱（Crosslinking MS）作为一种方法在过去的二十年里通过多个实验室的并行发展已经相当成熟，证明了它在复杂混合物中的蛋白质结构测定、构象分析和蛋白质相互作用图谱绘制方面的适用性。交联质谱已成为一种备受重视和常规应用的工具，尤其是在结构生物学中。因此，共同体致力于制定方法和报告标准是及时的。本白皮书建立在一个开放进程的基础上，该进程包括自2015年以来在社区会议上举行的一些活动，并确定了交联MS的各个方面，作为交联MS标准倡议的一部分，应为这些方面制定指导方针。
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英文标题：
《Towards Increased Reliability, Transparency and Accessibility in
Crosslinking Mass Spectrometry》
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作者：
Alexander Leitner, Alexandre M.J.J. Bonvin, Christoph H. Borchers,
Robert J. Chalkley, Julia Chamot-Rooke, Colin W. Combe, J\"urgen Cox,
Meng-Qiu Dong, Lutz Fischer, Michael G\"otze, Fabio C. Gozzo, Albert J. R.
Heck, Michael R. Hoopmann, Lan Huang, Yasushi Ishihama, Andrew R. Jones, Nir
Kalisman, Oliver Kohlbacher, Karl Mechtler, Robert L. Moritz, Eugen Netz,
Petr Novak, Evgeniy Petrotchenko, Andrej Sali, Richard A. Scheltema, Carla
Schmidt, David Schriemer, Andrea Sinz, Frank Sobott, Florian Stengel,
Konstantinos Thalassinos, Henning Urlaub, Rosa Viner, Juan A. Vizcaino, Marc
R. Wilkins, Juri Rappsilber
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最新提交年份：
2020
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分类信息：
一级分类：Quantitative Biology 数量生物学
二级分类：Other Quantitative Biology 其他定量生物学
分类描述：Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要：
Crosslinking mass spectrometry (Crosslinking MS) has substantially matured as a method over the last two decades through parallel development in multiple labs, demonstrating its applicability for protein structure determination, conformation analysis and mapping protein interactions in complex mixtures. Crosslinking MS has become a much-appreciated and routinely applied tool especially in structural biology. Therefore, it is timely that the community commits to the development of methodological and reporting standards. This white paper builds on an open process comprising a number of events at community conferences since 2015 and identifies aspects of Crosslinking MS for which guidelines should be developed as part of a Crosslinking MS standards initiative.
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PDF链接：
https://arxiv.org/pdf/2007.00383
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