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摘要翻译：
生物学中结构的演化是由吸积和变化驱动的。吸积把不同的部分聚集在一起，形成更大的整体。变化为增长和创新提供了机会。在这里，我们回顾了从蛋白质和核酸到城市高层建筑结构的各种复杂程度上导致进化增长的“双重故事”的模式和过程。各部分最初是弱联系的，并有不同的关联。随着它们的多样化，它们相互竞争，并被选中进行表演。新出现的相互作用制约着它们的结构和关联。这导致部件自组织成具有紧密链接的模块。在第二个阶段，模块的变体进化并成为更高层次组织的新生成周期的新部分。进化基因组学和网络生物学支持结构模块创建的“双重故事”，并验证了驱动模块得失的最大丰度的进化原则。
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英文标题：
《Evolution of macromolecular structure: a 'double tale' of biological
accretion》
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作者：
Derek Caetano-Anoll\'es, Kelsey Caetano-Anoll\'es and Gustavo
Caetano-Anoll\'es
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最新提交年份：
2018
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分类信息：
一级分类：Quantitative Biology 数量生物学
二级分类：Other Quantitative Biology 其他定量生物学
分类描述：Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要：
The evolution of structure in biology is driven by accretion and change. Accretion brings together disparate parts to form bigger wholes. Change provides opportunities for growth and innovation. Here we review patterns and processes that are responsible for a 'double tale' of evolutionary accretion at various levels of complexity, from proteins and nucleic acids to high-rise building structures in cities. Parts are at first weakly linked and associate variously. As they diversify, they compete with each other and are selected for performance. The emerging interactions constrain their structure and associations. This causes parts to self-organize into modules with tight linkage. In a second phase, variants of the modules evolve and become new parts for a new generative cycle of higher-level organization. Evolutionary genomics and network biology support the 'double tale' of structural module creation and validate an evolutionary principle of maximum abundance that drives the gain and loss of modules.
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PDF链接：
https://arxiv.org/pdf/1805.06487
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