<p>【书名】Pharmaceutical Statistics Using SAS: A Practical Guide<br/>【作者】Alex Dmitrienko; Christy Chuang-Stein; Ralph B.; Sr.; Ph.d. D'agostino<br/>【出版社】SAS Publishing<br/>【版本】First edition <br/>【出版日期】February 26, 2007<br/>【文件格式】PDF (清晰电子书)<br/>【文件大小】3.6M (解压后)<br/>【页数】464 pages<br/>【ISBN出版号】159047886X<br/>【资料类别】SAS实用工具书<br/>【市面定价】$56<br/>【扫描版还是影印版】清晰电子书<br/>【是否缺页】否<br/>【关键词】beta regression model, proc glimmix, Wilcoxon Rank Sum<br/>【内容简介】 本书为制药领域专家撰写,介绍了如何将最新生物统计的技术应用于新药研发过程中。 <br/>【Amazon链接】<br/> <a href="http://www.amazon.com/Pharmaceutical-Statistics-Using-SAS-Practical/dp/159047886X">http://www.amazon.com/Pharmaceutical-Statistics-Using-SAS-Practical/dp/159047886X</a></p><p>【目录】 <br/> Chapter 1 Statistics in Drug Development <br/> Chapter 2 Modern Classification Methods for Drug Discovery <br/> Chapter 3 Model Building Techniques in Drug Discovery <br/> Chapter 4 Statistical Considerations in Analytical Method Validation <br/> Chapter 5 Some Statistical Considerations in Nonclinical Safety Assessment <br/> Chapter 6 Nonparametric Methods in Pharmaceutical Statistics <br/> Chapter 7 Optimal Design of Experiments in Pharmaceutical Applications <br/> Chapter 8 Analysis of Human Pharmacokinetic Data <br/> Chapter 9 Allocation in Randomized Clinical Trials<br/> Chapter 10 Sample-Size Analysis for Traditional Hypothesis Testing: Concepts and Issues<br/> Chapter 11 Design and Analysis of Dose-Ranging Clinical Studies <br/> Chapter 12 Analysis of Incomplete Data <br/> Chapter 13 Reliability and Validity: Assessing the Psychometric Properties of Rating Scales<br/> Chapter 14 Decision Analysis in Drug Development </p><p><br/>【整理书评】<br/> 本书通过一系列教程和实例介绍制药领域最新的数值分析技术,还提供了大量实用SAS Code用于解决实际问题。涉及的主题包括:<br/>drug discovery experiments to identify promising chemical compounds<br/>animal studies to assess the toxicological profile of these compounds<br/>clinical pharmacology studies to examine the properties of new drugs in healthy human subjects<br/>Phase II and Phase III clinical trials to establish therapeutic benefits of experimental drugs </p><p> </p><p>
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