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2014-11-18
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¡¾Abstract¡¿ Objective To investigate the dynamics of resistance to antibiotics of the P.aeruginosa separated from patients in our hospital from Jan 2001 to Dec£¬2003. Methods The characteriztion and sensitivity to antibiotics of P.aeruginosa were analysed using MicroScan WalkAway-40 system.Results 107 strains of P.aeruginosa were separated and characterized during the three years. The rates of resistance to antibiotics were Imipenem 0.9%£¬Amikacin 5.6%£¬ Piperacillin/Tazobactan 6.5%£¬ Ceftriaxone 63.6%£¬ Cefotaxime 38.3%£¬Aztreonam 25.2%.From 2001 to 2003£¬the resistance rate to Cefotaxime rose from 33.3% to 44.4%£¬ Ceftriaxone from 48.1% to 68.9%.The resistance rate to ¦Â-lactam antibiotics£¬decreased from 22.2% to 15.6%£¬showed dropping tendency.Conclusion P.aeruginosa showed good sensitivity to Carbapenems£¬Aminoglycosides£¬¦Â-lactam antibiotics£¬but resistance rates to third-generation Cephalosporins were higher in our hospital than whole nation in 2001 and 2002. The results suggested that the resistance of P.aeruginosa to antibiotics should be continuously monitored.
¡¾Key words¡¿ P.aeruginosa£» sensitivity£»resistance to drugs£»determination of drug sensitivity£»microorganism
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