56只新西兰大白兔随机分为3组用于胸部损伤特点及心肺功能研究:假致伤组12只;实验一组22只;实验二组22只。伤前及伤后3h、6h、12h抽取动脉血行心肌标记物及血气分析(CK-MB,cTnI;PO2,PCO2,乳酸)。
审稿人问题:Theauthors state that they performed a repeated measures ANOVA, but given that they have both within and between subject measures, what they needed to performwas a mixed repeated measures ANOVA. Reviewer has some concerns with the statistical analyses such as the treatment of the sham group, the handling of uneven between groups sizes. 审稿人让我使用混合模型并问我假致伤组只有12只动物,采用什么统计方法处理组间的不均衡性?


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