摘要翻译:
所有球形病毒的蛋白质壳或衣壳都采用二十面体对称性。本文提出了一个病毒自组装的统计热力学模型。我们发现二十面体对称性不是由结构相同的蛋白质亚基构建的病毒衣壳所期望的,这种对称性需要(至少)蛋白质的两个内部“开关”构型。我们的结果表明二十面体对称性不是自由能最小化的一般结果,而是需要优化衣壳蛋白的内部结构参数。
---
英文标题:
《Viral self-assembly as a thermodynamic process》
---
作者:
Robijn F. Bruinsma, William M. Gelbart, David Reguera, Joseph Rudnick
and Roya Zandi
---
最新提交年份:
2003
---
分类信息:
一级分类:Physics 物理学
二级分类:Soft Condensed Matter 软凝聚态物质
分类描述:Membranes, polymers, liquid crystals, glasses, colloids, granular matter
膜,聚合物,液晶,玻璃,胶体,颗粒物质
--
一级分类:Physics 物理学
二级分类:Other Condensed Matter 其他凝聚态物质
分类描述:Work in condensed matter that does not fit into the other cond-mat classifications
在不适合其他cond-mat分类的凝聚态物质中工作
--
一级分类:Physics 物理学
二级分类:Statistical Mechanics 统计力学
分类描述:Phase transitions, thermodynamics, field theory, non-equilibrium phenomena, renormalization group and scaling, integrable models, turbulence
相变,热力学,场论,非平衡现象,重整化群和标度,可积模型,湍流
--
一级分类:Quantitative Biology 数量生物学
二级分类:Other Quantitative Biology 其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
--
---
英文摘要:
The protein shells, or capsids, of all sphere-like viruses adopt icosahedral symmetry. In the present paper we propose a statistical thermodynamic model for viral self-assembly. We find that icosahedral symmetry is not expected for viral capsids constructed from structurally identical protein subunits and that this symmetry requires (at least) two internal "switching" configurations of the protein. Our results indicate that icosahedral symmetry is not a generic consequence of free energy minimization but requires optimization of internal structural parameters of the capsid proteins.
---
PDF链接:
https://arxiv.org/pdf/cond-mat/0211390


雷达卡



京公网安备 11010802022788号







