R的glmmLasso中的control函数里面的method如是提到:
two methods for the computation of the random-effects variance-covariance pa-
rameter estimates can be chosen, an EM-type estimate and an REML-typees-
timate. The REML-type estimate uses bobyqa function for optimization.
Defaultis EM.
其中,EM我倒是能明白,但是广义线性混合模型,怎么做REML-type估计?
见附件第5页