nonlinear mixed model convergence problem

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nonlinear mixed model estimation done with the original data set, but not converge with some selected sub data sets

any simple idea about how to solve? (using R built in nlme; and I've tried to change the initial value by using those estimated by nonlinear model without random effect, but not very effective)

Thanks.

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关键词：mixed model Convergence Nonlinear converge nonlinea effective original selected problem initial