你好,欢迎来到经管之家 [登录] [注册]

设为首页 | 经管之家首页 | 收藏本站

北京大学药学院化学生物学专业硕士研究生导师信息:李庆

发布时间:2015-01-06 来源:人大经济论坛
李庆:副教授,硕士生导师 电话:010-82801714 E-mail: qli@bjmu.edu.cn 通信地址:北京市海淀区学院路38号药学楼522室 邮编:100191 1983.9-1987.7,兰州大学化学系有机化学专业,学士学位;1987.8-1991.11,大庆石油化工总厂研究院,助理工程师;1991.11-1996.8,大庆油田设计院,工程师;1993.9-1996.7,天津大学化学系精细化工专业,硕士学位;1996.9-1999.7,北京医科大学药学院药物化学专业,博士学位。自1999年至今,北京大学医学部药学院化学生物学系工作。目前主要开展抗粘附多价寡糖及糖-肽杂合物的合成研究, 设计合成了结构多样的多价寡糖及糖-肽杂合物,其中四价乳糖Gu-4具有良好的抗白细胞-内皮细胞粘附活性,作为药物候选分子在对大鼠的重症烧伤休克、脓毒症及关节炎的治疗中已显示了良好的效果。 目前在研课题: 1.乳糖衍生物抗粘附新靶点的发现及其抗炎机制的研究 (90713004),国家自然科学基金重大研究计划基于化学小分子探针的信号转导过程研究培育项目,2008.1~2010.12。 2. 新型多配体型杂合糖簇的设计、合成及杂簇螯合效应的探索(21172015),国家自然科学基金面上项目,2012.01~2015.12。。 近年发表的相关论文: 1. Qing Li, Bin Su, Hui Li, Xiang-Bao Meng, Meng-Shen Cai, Zhong-Jun Li, Ta-Lin Suo, Rou-Li Zhou, Synthesis and potential activity in anti-metastasis of spacer armed 2-acetamido-2-deoxy-4-O-b-D-galactopyranosyl-D-glucosides and their dimers, Carbohydrate Research, 2003, 338, 207-217. 2. Shu Chun Li, Li Min Niu, Hui Li, Zhong Jun Li, Qing Li*, Synthesis of RGD-aPEG-Lactoside, a Potential Anti-metastasis Glycoconjugate, Chin. Chem. Lett., 2004, 15, 532-534. 3. Zhao-Jun Yin, Qing Li*, Xiang-Bao Meng and Zhong-Jun Li*, Design and Synthesis of Novel Multivalent Mannosides Targeting Mannose Receptor, Carbohydrate Research, 2007, 342, 2729-2734. 4. Chen Li, Xiang-Bao Meng, Xiao-Feng Jin, Zhong-Jun Li and Qing Li* , Synthesis of allyl 4-O-{3-deoxy-3-[4-benzylaminocarbonyl-1H-(1,2,3)-triazol-1-yl]-β-D-galactopyranosyl}-2-deoxy-2-acetamido-β-D-glucopyranoside as a potential inhibitor of   galectin-3, Journal of Chinese Pharmaceutical Sciences, 2008, 17, 209-214. 5. Zhihui Zhao & Qing Li & Jiale Hu & Zhongjun Li & Jinghua Liu & Aihua Liu & Peng Deng & Lin Zhang & Xiaowei Gong & Kesen Zhao & Shuangquan Zhang & Yong Jiang, Lactosyl derivatives function in a rat model of severe burn shock by acting as antagonists against CD11b of integrin on leukocytes, Glycoconjugate J., 2009, 26, 173-188. 6.Yu Zheng, Xiang-bao Meng, Shu Chun Li, He-Qing Hang, Zhong-jun Li*, Qing Li* Synthesis and anti-tumor activities of 5-carbohydrate modified cyclophosphamide derivates, Journal of Chinese Pharmaceutical Sciences, 2010, 19, 327-340. 7.  Qing Li, Yuetao Zhao, Xiangbao Meng, Tingting Yan, Zhihui Zhao, Zhongjun Li, Synthesis of two multivalent lactosides with anti-adhesive activity and their fluorescein-labeled and biotin-labeled derivatives, Journal of Chinese Pharmaceutical Sciences, 2011, 20, 325-334. 8.李中军, 李庆,赵智辉,孟祥豹,李树春,一类抗粘附活性的乳糖簇及其荧光标记物, 中国专利ZL 200610078665X. 9.赵智辉,陈元,褚键,王良哲,李中军, 李庆,乳糖衍生物的新用途,中国专利 ZL 03112879.3.
经管之家“学道会”小程序
  • 扫码加入“考研学习笔记群”
推荐阅读
经济学相关文章
标签云
经管之家精彩文章推荐